A study by a team of researchers at the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) and Shriners Hospital for Children has made a technological advancement toward accelerating the discovery of drug targets for obesity, type II diabetes and other metabolic diseases. The novel experimental and computational workflow involves the first use of rodent … [Read more...]
Weight Management News
Abdominal fat a key cancer driver for postmenopausal women
Body fat distribution in the trunk is more important than body weight when it comes to cancer risk in postmenopausal women, according to a study presented at the ESMO 2017 Congress in Madrid. The findings put a new spin on weight management priorities for women in this this age-group, who are prone to abdominal weight gain, said study investigator Line Mærsk Staunstrup, … [Read more...]
Gene therapy via skin could treat many diseases, even obesity
A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat many human diseases. In the August 3, 2017 issue of the journal Cell Stem Cell, the researchers provide "proof-of-concept." They describe a … [Read more...]
Young adult obesity: A neglected, yet essential focus to reverse the obesity epidemic
The overall burden of the U.S. obesity epidemic continues to require new thinking. Prevention of obesity in young adults, while largely ignored as a target for prevention and study, will be critical to reversing the epidemic, says William Dietz, MD, PhD, Chair of the Sumner M. Redstone Global Center for Prevention and Wellness at the Milken Institute School of Public Health at … [Read more...]
Can smelling your food make you fat?
Our sense of smell is key to the enjoyment of food, so it may be no surprise that in experiments at the University of California, Berkeley, obese mice who lost their sense of smell also lost weight. What's weird, however, is that these slimmed-down but smell-deficient mice ate the same amount of fatty food as mice that retained their sense of smell and ballooned to twice … [Read more...]
Newly found, ‘thrifty’ genetic variant influences Samoan Obesity
The Samoas' world-leading rate of obesity is a recent phenomenon, heavily influenced by the globe's rapid shift to calorie-rich, processed foods and more sedentary lifestyles. A new study, however, suggests nearly half of Samoans have a newly identified and significant genetic variant that contributes to obesity risk; a variant that had remained undiscovered until … [Read more...]
The Trick To Turn White Fat Brown!
A signaling pathway in fat cells may one day provide the key to better treatments for obesity, according to new research by scientists in the Perelman School of Medicine at the University of Pennsylvania. They reported their findings online ahead of print in Genes & Development. Ordinary fat cells, also called white adipocytes, stuff themselves with fat molecules … [Read more...]
Insulin Resistance Reversed By Removal Of Protein
By removing the protein galectin-3 (Gal3), a team of investigators led by University of California School of Medicine researchers were able to reverse diabetic insulin resistance and glucose intolerance in mouse models of obesity and diabetes. By binding to insulin receptors on cells, Gal3 prevents insulin from attaching to the receptors resulting in cellular insulin … [Read more...]
Sleep deprivation may cause people to eat more calories
Sleep deprivation may result in people consuming more calories during the following day, according to a systematic review and meta-analysis led by researchers at King's College London. The meta analysis combined the results of many previous small intervention studies to produce a more robust answer and found that sleep-deprived people consumed an average of 385 kcal per … [Read more...]
Workplace Workout Can Do Wonders!
Employees who participate in a workplace weight management program—even those without significant weight loss—have reduced health care costs and improved quality of life (QOL), reports a study in the November Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM). Tzeyu L. … [Read more...]
Child Obesity On An Alarming Rise!
Researchers' global estimates indicate that by 2025, some 268 million children aged 5 to 17 years may be overweight, including 91 million obese, assuming no policy interventions have proven effective at changing current trends. Timed to coincide with this year's World Obesity Day, which is observed on October 11, investigators have also released data anticipating that … [Read more...]
Don’t blame your genes if you’re not losing weight!
You might be able to blame your genes for weighing more and increasing your risk of obesity, but you can no longer blame your genes for failing to lose weight, a comprehensive study has found. Carriers of the FTO gene are known to be on average 3 kilos (6.6lbs) heavier and 70% more likely to be obese. However, researchers at Newcastle University, publishing in The … [Read more...]
Children Should Eat Less Than 25 Grams Of Added Sugars Daily
Children ages 2 to 18 should eat or drink less than six teaspoons of added sugars daily, according to the scientific statement recommending a specific limit on added sugars for children, published in the American Heart Association journal Circulation. Six teaspoons of added sugars is equivalent to about 100 calories or 25 grams. "Our target recommendation is the same … [Read more...]
A New Approach Can Prevent Teen Obesity & Eating Disorders
A single approach can prevent both obesity and eating disorders in teenagers, according to new guidelines from the American Academy of Pediatrics. Scientific evidence summarized in the new recommendations shows that physicians and parents can ward off problems at both ends of the weight spectrum by avoiding focusing teens' attention on weight or dieting, and instead … [Read more...]
‘Healthy Obesity’ May Be A Myth
The term "healthy obesity" has gained traction over the past 15 years, but scientists have recently questioned its very existence. A new study provides further evidence against the notion of a healthy obese state, revealing that white fat tissue samples from obese individuals classified as either metabolically healthy or unhealthy actually show nearly identical, abnormal … [Read more...]
Proved: Exercise Does More Good If You Believe It Will
Everyone knows exercise is supposed to be good for your health, but is the belief that exercise will have a positive effect more important for our well-being than the exercise itself? The psychologist Hendrik Mothes from the University of Freiburg's Department of Sport Science and his team have conducted a study demonstrating that test subjects derive more psychological as well … [Read more...]
Do You Feel Hungry Even After A Meal?
The brain's reward centers in severely obese women continue to respond to food cues even after they've eaten and are no longer hungry, in contrast to their lean counterparts, according to a recent study by a multidisciplinary team at UT Southwestern Medical Center. The study, published recently in the journal Obesity, compared attitudes and the brain activity of 15 … [Read more...]
Multiply The Fat Burnt During Exercise
When we exercise, our body’s oxidation of fat and carbohydrates depends on the intensity and duration of the activity. A new study analyses the effect of consuming an alkaloid, p-synephrine, on the burning of lipids and refutes the value of “miracle” diets: it is not possible to lose more than a kilogramme of fat per month. New research published in the British Journal of … [Read more...]
Obesity May Be A Disease Of The Brain
Obesity may ultimately be a disease of the brain, involving a progressive deterioration of various cognitive processes that influence eating. Researchers at Macquarie University have now shown that memory inhibition -- the useful ability to 'block out' memories that are no longer useful, which depends on a brain area called the hippocampus -- is linked to dietary excess. … [Read more...]
Early To Bed Cuts Risk Of Obesity Later
Preschoolers who are regularly tucked into bed by 8 p.m. are far less likely to become obese teenagers than young children who go to sleep later in the evening, new research has found. Bedtimes after 9 p.m. appeared to double the likelihood of obesity later in life, according to a study from The Ohio State University College of Public Health. "For parents, this … [Read more...]
Is Your Brain Fueling You to Overeat?
The findings offer clues in Alexander Johnson's quest to unpack the interconnected mechanisms of overeating and obesity. Obesity is an epidemic domestically -- more than a third of Americans are considered to be obese -- and a growing health problem in other parts of the world. "In today's society we are bombarded with signals to eat, from fast-food commercials to the … [Read more...]
How lifestyle intervention for weight loss affects birth rates in women?
Women who are overweight or obese pose an ongoing challenge for the fertility clinic. Many studies show that these patients are at increased risk of infertility and are less likely than normal-weight women to conceive after fertility treatment. For example, ovulating sub-fertile women with a body mass index (BMI) of 29 kg/m2 or higher have been found in one study to have a 4% … [Read more...]
Switch-Off Your Cravings
Eating a type of powdered food supplement, based on a molecule produced by bacteria in the gut, reduces cravings for high-calorie foods such as chocolate, cake and pizza, a new study suggests. Scientists from Imperial College London and the University of Glasgow asked 20 volunteers to consume a milkshake that either contained an ingredient called inulin-propionate … [Read more...]
Calorie-burning Pathway found in Fat Cells
Investigators at Dana-Farber Cancer Institute in collaboration with scientists at the University of California, Berkeley, have identified a natural molecular pathway that enables cells to burn off calories as heat rather than store them as fat. This raises the possibility of a new approach to treating and preventing obesity, diabetes, and other obesity-linked metabolic … [Read more...]
Greater Risk of Heart Failure among Overweight Youth
It comes down to starting healthy habits early. Fortunately, it's never too late to adopt a healthier lifestyle, and losing weight is great for reducing your risk of heart attack. But you can still be at a higher risk for other heart problems if you're late in changing your habits. Excessive weight at a young age puts one at a far higher risk of heart failure as … [Read more...]
Children drinking sports drinks have risk of obesity
A high proportion of 12-14 year olds are regularly consuming sports drinks socially, increasing their risk of obesity and tooth erosion, concludes a Cardiff University School of Dentistry survey. Published today in the British Dental Journal, the survey looked at 160 children in four schools across South Wales and concluded that children are attracted to sports drinks … [Read more...]
Harsh parenting may lead to obesity in young women
The adolescent years can be full of changes, whether physical, emotional, or familial. A new study by Iowa State University researchers suggests that when these years include prolonged periods of food insecurity coupled with harsh parenting practices, females are prone to obesity in early adulthood. "When females who are normal weight in their early adolescence … [Read more...]
Adolescent weight linked to heart failure in early middle age
Surprisingly, the increased risk of heart failure was found in who were within the normal body weight range (a body mass index of 18.5 to 25) in adolescence, with an increased risk starting in those with a BMI of 20 and rising steeply to a nearly ten-fold increased risk in those who were very obese, with a BMI of 35 or over. The study, which is published in the European … [Read more...]
Philadelphia to bring in ‘soda tax’ to fight obesity
Philadelphia has introduced a levy on carbonated sugary drinks, despite a multi million-dollar campaign by the beverage industry to block it. It will become the first major US city to implement a so-called "soda tax", which supporters say will improve the health of 1.5 million residents. But opponents say it will hurt small businesses and poorer people. The measure will come … [Read more...]
Study compares effectiveness of weight-loss drugs
In an analysis that included nearly 30,000 overweight or obese adults, compared with placebo, orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide were each associated with achieving at least 5 percent weight loss at 52 weeks, and phentermine-topiramate and liraglutide were associated with the highest odds of achieving at least 5 percent weight … [Read more...]
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