(Ivanhoe Newswire)
-- A new genetically engineered material made of human
proteins speeds recovery time and improves results in lumbar spine fusions at
greater rates than originally believed, according to Charles Rosen, M.D., a
spine surgeon at the University of California at Irvine.
The new material is called bone morphogenic protein (BMP). Doctors spent
decades trying to isolate and produce the exact substance in humans that causes
broken bones to heal and spines to fuse upon operation. Recent advances in
genetic engineering allow BMP's production in concentrated form.
Two years ago, the FDA approved the use of BMP for lumbar spine fusions, and
preliminary findings proved it to result in successful fusions 95 percent of the
time.
Dr. Rosen says his research based on his patients' spinal fusion outcomes
from the past two years shows that with BMP, lumbar spine fusion patients
recover twice as quickly than with traditional surgery. Recovery time was cut
from three to five months to two to four weeks. Dr. Rosen says spines fuse
successfully 100 percent of the time, as opposed to the 80-percent success rate
with traditional bone graft surgery.
Traditional bone graft back surgery involves replacing degenerating discs or
vertebrae with bone taken from a patient's own hip. Dr. Rosen says it is
painful, can have multiple complications, and often fails. He says the new
method with BMP halves the time to fusion and is much less painful than taking
chunks of bone from a patient's hip.
Dr. Rosen says, "We're only a short time away from using BMP for all sorts of
bone injuries from fractures to bone diseases to joint reconstruction. BMP will
revolutionize the way bones are treated." He tells Ivanhoe, "With BMP, bone
grafts will become obsolete for spinal surgery. Having done spine surgery for 15
years and having to deal with the non-unions that occur, to me, it's utterly
astounding to have a virtually 100-percent fusion rate using this. It' s unheard
of in the history of spine surgery."
Dr. Rosen adds, "My opinion is that over the next five years, I think it will
become the standard for spine fusions. It is not now, but as the results come
out from people like me and other people who just do spine surgery, I think it's
going to become obvious that this really should be the standard because it fuses
so well, so extensively, so quickly, and you obviate the need for painful bone
graft, which is horrible."
Dr. Rosen is also using BMP fusion for neck surgery. He says, "The new
indications of using it in the cervical spine are as good."
SOURCE: Ivanhoe interview with Charles Rosen, M.D., of the University of
California at Irvine