Roseroot: Miraculous Herb to manage Depression and Mental fatigue


Roseroot: Miraculous Herb to manage Depression and Mental fatigueRecent researches has concluded the miraculous qualities of roseroot herb for treating depression and mental fatigue. Rhodiola rosea (commonly golden root, rose root, roseroot, western roseroot, Aaron's rod, Arctic root, king's crown, lignum rhodium, orpin rose) is a perennial flowering plant in the family Crassulaceae. It grows in cold regions of the world, including much of the Arctic, the mountains of Central Asia, scattered in eastern North America from Baffin Island to the mountains of North Carolina, and mountainous parts of Europe, such as the Alps, Pyrenees, and Carpathian Mountains, Scandinavia, Iceland, Great Britain and Ireland. It grows on sea cliffs and on mountains at altitudes up to 2280 meters. Several shoots grow from the same thick root. Shoots may reach 5 to 35 cm in height. R. rosea is dioecious � having separate female and male plants.

Some studies have found support for it having antidepressant effects. It is not approved by the U.S. Food and Drug Administration (FDA) to cure, treat, or prevent any disease. In fact, the FDA has forcibly removed some products containing R. rosea from the market due to disputed claims that it treats cancer, anxiety, influenza, the common cold, bacterial infections, and migraines.

R. rosea may be effective for improving mood and alleviating depression. Pilot studies on human subjects showed it improves physical and mental performance, and may reduce fatigue.
 

In Russia and Scandinavia, R. rosea has been used for centuries to cope with the cold Siberian climate and stressful life. Such effects were provided with evidence in laboratory models of stress using the nematode C. elegans, and in rats in which Rhodiola effectively prevented stress-induced changes in appetite, physical activity, weight gain and the estrus cycle.

The plant has been used in traditional Chinese medicine, where it is called h�ng jǐng tiān. The medicine can be used to prevent altitude sickness. The aerial portion is consumed as food in some parts of the world, sometimes added to salads.

Phytochemicals and health effects


Research regarding R. rosea efficacy is contradictory. While some evidence suggests that the herb may be helpful for enhancing physical performance and alleviating mental fatigue, methodological flaws limit accurate assessment of efficacy. A rigorously-designed well reported RCT that minimizes bias is needed to determine true efficacy of R. rosea for fatigue.

Scientists have identified about 140 chemical compounds in the subterranean portions of R. rosea. Rhodiola roots contain phenols, rosavin, rosin, rosarin, organic acids, terpenoids, phenolcarbonic acids and their derivatives, flavonoids, anthraquinones, and alkaloids.

The chemical composition of the essential oil from R. rosea root growing in different countries varies. For example, rosavin, rosarin and rosin at their highest concentration according to many tests can be found only in R. rosea of Russian origin; the main component of the essential oil from Rhodiola growing in Bulgaria are geraniol and myrtenol; in China the main components are geraniol and 1-octanol; and in India the main component is phenylethilic alcohol. Cinnamic alcohol was discovered only in the sample from Bulgaria.

Roseroot: Miraculous Herb to manage Depression and Mental fatigueAlthough rosavin, rosarin, rosin and salidroside (and sometimes p-tyrosol, rhodioniside, rhodiolin and rosiridin) are among suspected active ingredients of R. rosea, these compounds are mostly polyphenols. There is no evidence that these chemicals have any physiological effect in humans that could prevent or reduce risk of disease.

Although these phytochemicals are typically mentioned as specific to Rhodiola extracts, there are many other constituent phenolic antioxidants, including proanthocyanidins, quercetin, gallic acid, chlorogenic acid and kaempferol.

A herb used in traditional European folk medicine for over 3,000 years could be a potential treatment option for depression, according to the results of a new study. The study, published in Phytomedicine, was led by Dr. Jun J. Mao, an associate professor of family medicine, community health and epidemiology at the Perelman School of Medicine of the University of Pennsylvania.

Rhodiola rosea, also referred to as roseroot, has been used in traditional folk medicine to promote work endurance, increase longevity and promote resistance to several health conditions including fatigue, altitude sickness and depression. Ancient Greeks, Vikings, Caucasians, prehistoric Siberians and Mongolians, and ancient Chinese emperors were all taken with the medicinal properties of the wild herb Rhodiola rosea (golden root or roseroot). Many centuries after it was introduced to Siberia, people there still say those who drink roseroot tea will live to be 100. Now new research has shown that this ancient medicinal herb may also be effective in treating depression.

Since 1960, more than 180 studies have been done to gauge the efficacy of roseroot in promoting health. Now medical researchers at the University of Pennsylvania have done the �first randomized, double-blind, placebo-controlled, comparison trial of oral R. rosea extract versus conventional antidepressant therapy of mild to moderate� depression. This latest research, along with previous studies, found that the ancients were right to be enamored with roseroot: It works not just in reducing some symptoms of depression, but it also gave �significant reductions in fatigue, depression, and performance ratings� in two groups tested in another study.
 

In ancient times, Siberians found the root so valuable they would trade it for wine, fruit and honey �In Siberia to this day, it is said that people who drink Rhodiola rosea tea will live to be more than 100,� the MDidea article states. �The herb still is given to newlyweds to assure fertility and the birth of healthy children. For centuries the details of how and where to harvest the wild root were a closely guarded secret among members of certain Siberian families, who would transport Rhodiola rosea down ancient trails in the Altai and Caucasus mountains and trade it for Georgian wine, fruit, and honey.�

Roseroot: Miraculous Herb to manage Depression and Mental fatigue�Rhodiola has a legendary history dating back thousands of years,� says herbwisdom.com. �In 77 A.D., the Greek physician Dioscorides documented the medical applications of the plant, which he then called rodia riza, in his classic medical text De Materia Medica. The Vikings depended on the herb to enhance their physical strength and endurance, while Chinese emperors sent expeditions to Siberia to bring back the golden root� for medicinal preparations. The people of central Asia considered a tea brewed from Rhodiola rosea to be the most effective treatment for cold and flu. Mongolian physicians prescribed it for tuberculosis and cancer.�

Clinical trials supporting therapeutic claims are of limited quality. R. rosea may have beneficial effects in managing mild to moderate depression and mental fatigue. Results from trials evaluating adaptogenic properties and physical endurance are equivocal.

Three cinnamyl alcohol vicianosides (rosavin, rosin, rosarin) have been found to be specific to R. rosea.These 3 substances, along with rosiridin and salidroside, are the 5 marker compounds that must be present to reliably identify R. rosea. R. rosea extracts used in most clinical trials were standardized to a minimum of 3% rosavins and 0.8% to 1% salidroside, the naturally occurring ratio in the plant.

The phenylethanol derivatives salidroside (rhodioloside) and tyrosol have been found in the underground part of the plants. Flavonoids in R. rosea include rodiolin, rodinin, rodiosin, acetylrodalgin, and tricin, as well as other catechins and proanthocyanidins. Monoterpenes include rosiridol and rosaridin, and triterpenes include daucosterol and beta-sitosterol.Terpenes and volatile compounds have been isolated from R. rosea and include the essential oil components of monoterpene hydrocarbons, monoterpene alcohols and straight-chain aliphatic alcohols, n-decanol, geraniol (which is responsible for the rose-like odor), linalool, nonanal, decanal, nerol, and cinnamyl alcohol. Phenolic acids, including chlorogenic, hydroxycinnamic, and gallic acids, are also present.

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Dated 17 July 2015


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