Patients who expressed the tumor antigen NY-ESO-1 had more aggressive cancers and were more likely to die early from their disease, according to a large study conducted by Roswell Park Cancer Institute researchers and published online ahead of print in the journal Gynecologic Oncology. "This is the largest study of NY-ESO-1 expression in ovarian cancer patients, and … [Read more...]
Cancer News
Vitamin D, calcium supplementation among older women does not significantly reduce risk of cancer
Among healthy postmenopausal women, supplementation with vitamin D3 and calcium compared with placebo did not result in a significantly lower risk of cancer after four years, according to a study published by JAMA. About 40 percent of the U.S. population will have a cancer diagnosis at some point during their lives. Evidence suggests that low vitamin D status may … [Read more...]
Cancer overtakes heart disease as the main cause of death in 12 European countries
Although diseases of the heart and blood vessels (cardiovascular disease, CVD) kill more people worldwide than anything else, with 17.3 million deaths globally, cancer has now overtaken CVD as the main cause of death in 12 European countries. New data on the burden of CVD in Europe for 2016, which are published today (Monday) in the European Heart Journal, show that in … [Read more...]
Veterans returning from Middle East face higher skin cancer risk
Soldiers who served in the glaring desert sunlight of Iraq and Afghanistan returned home with an increased risk of skin cancer, due not only to the desert climate, but also a lack of sun protection, Vanderbilt dermatologist Jennifer Powers, M.D., reports in a study published recently in the Journal of Investigative Dermatology. "The past decade of United States combat … [Read more...]
Lung cancer: Protein as potential tool for predicting survival
The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumour surgically removed. This is substantiated by the results of a study conducted under the direction of the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna General Hospital, together with MedUni Graz and the University … [Read more...]
Alcohol intake associated with increased risk of melanoma
Alcohol intake is associated with higher rates of invasive melanoma among white men and women, new research shows. White wine carried the most significant association, and the increased risk was greater for parts of the body that receive less sun exposure. The study has been published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for … [Read more...]
New Protein Sheds Light On How Diabetes Drug Prevents Tumors
Researchers at University of California San Diego School of Medicine have identified a previously unknown mechanism that helps fortify the structure and tight junctions between epithelial cells -- a basic cell type that lines various body cavities and organs throughout the body, forming a protective barrier against toxins, pathogens and inflammatory triggers. Breaches of this … [Read more...]
Blood Test Could Predict Best Treatment For Lung Cancer
A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment, according to new research published in Nature Medicine. Scientists, based at the Cancer Research UK Manchester Institute at The University of Manchester, isolated tumor cells that had broken away from the main cancer -- known as circulating tumour cells (CTCs) -- from … [Read more...]
Low Vitamin D Levels linked to Higher Risk of Bladder Cancer
Vitamin D deficiency is associated with an increased risk of developing bladder cancer, according to a systematic review of seven studies presented at the Society for Endocrinology annual conference in Brighton. Though further clinical studies are needed to confirm the findings, the study adds to a growing body of evidence on the importance of maintaining adequate vitamin D … [Read more...]
Cold Medicine Could Stop Cancer Spread, Study Reveals
Hokkaido University researchers have discovered that a nonsteroid anti-inflammatory drug used for treating colds suppresses the spread of bladder cancers and reduces their chemoresistance in mice, raising hopes of a future cure for advanced bladder cancers. Bladder cancer is the seventh most common cancer in males worldwide. Every year, about 20,000 people in Japan are … [Read more...]
Roadmap to get new cancer scans into clinic
A team of international scientists has outlined key recommendations for a global standard for scanning biomarkers in cancer -- to bridge the gap between research and the clinic, according to a new paper published in Nature Reviews Clinical Oncology today. Scans have transformed the way that doctors treat cancer patients and are integral to most key treatment decisions -- … [Read more...]
Cancer’s ‘invisibility cloak’: How It Works?
UBC researchers have discovered how cancer cells become invisible to the body's immune system, a crucial step that allows tumors to metastasize and spread throughout the body. "The immune system is efficient at identifying and halting the emergence and spread of primary tumors but when metastatic tumors appear, the immune system is no longer able to recognize the cancer … [Read more...]
Targeting Fat To Treat Cancer
Fat isn't just something we eat: it may also lie at the heart of a new approach to treating cancer. Cells create their own fat molecules to build their plasma membranes and other critical structures. Now, researchers at the Salk Institute, along with academic and industry collaborators, have found a way to obstruct this instrumental process to stifle cancer's growth, … [Read more...]
A Cardioprotective Chemotherapy Drug Can Have Negative Effects On Heart
A potent chemotherapy drug can be life saving for children with cancer, but a new review highlights how it can have long-lasting negative effects on the heart. The review, which is published in the British Journal of Clinical Pharmacology, also indicates that this chemotherapy-related heart damage may be prevented by a cardioprotective drug. Advances in cancer therapy have … [Read more...]
Impact of cancer screening in California over past 15 years
A new report from the UC Davis Institute for Population Health Improvement (IPHI) shows the impact of cancer screening over the past 15 years, identifying areas where increased screening and other cancer-control efforts would save lives and significantly benefit population health. The CalCARES report uses heat maps to show areas with higher proportions of particular … [Read more...]
A Mechanism That Allows Cancer To Survive Without Glucose
The main goal of a tumour cell is, above all, to survive, even at the cost of damaging the health of the organism to which it belongs. To do this, it is equipped with skills that healthy cells do not have, including the ability to continue surviving when glucose levels are very low. This could be one of the reasons why widely-used anti-angiogenic agents often fail to eliminate … [Read more...]
Skin Cancer Patients Still Too Likely To Sunburn
A recent study by researchers at Johns Hopkins concludes that a substantial number of people with a history of the most frequent kind of non-melanoma skin cancers still get sunburned at the same rate as those without previous history, probably because they are not using sun-protective methods the right way or in the right amounts. The findings, which were based on … [Read more...]
New Therapeutic Avenue in the Fight Against Cancer
A team of researchers led by professor Jean-Christophe Marine (VIB-KU Leuven) has identified NEAT1, a non-coding RNA, as a potential therapeutic target in the fight against cancer. In collaboration with the Cédric Blanpain lab (ULB), VIB researchers have shown that NEAT1 plays an important role in the survival of highly dividing cells -- and in particular of cancer cells. These … [Read more...]
Women with BRCA1 at High Risk of Uterine Cancer
Women who carry the BRCA1 gene mutation that dramatically increases their risk of breast and ovarian cancers are also at higher risk for a lethal form of uterine cancer, according to a study led by a Duke Cancer Institute researcher. This newly defined risk -- the first to show a conclusive link between the BRCA1 gene mutation and a small but significant chance of … [Read more...]
New Breakthrough in Brain Tumor Research
Scientists at Newcastle University, UK, have made a pioneering breakthrough in the understanding of how a fatal brain tumor grows -- which could lead to improved treatments for patients. Experts have found cells within the malignant brain tumor, glioma, rely on fats to fuel growth. This contradicts previous scientific belief that tumor cells require mainly sugars to … [Read more...]
New method developed to wipe out cancerous tumors
Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells. His discovery, described in a new study in The Journal of Clinical Oncology, may tremendously help people with inoperable or hard-to-reach tumors, as well as young children stricken with cancer. Gdovin's top-tier research involves … [Read more...]
3D kidney helps doctors save woman’s organ
Doctors and scientists at Intermountain Medical Center in Salt Lake City printed and used a 3D kidney to help save a patient's organ during a complicated tumor-removal procedural. The 3D-printed model allowed doctors to study the patient's kidney in 3D to determine how to best remove the tumor as it was located in a precarious location adjacent to vital arteries and … [Read more...]
Olive Oil: Mycobacterium for cancer treatment
Researchers at the Universitat Autònoma de Barcelona (UAB) with the collaboration of the Institute for Bioengineering of Catalonia (IBEC), led by the professor of the UAB Department of Genetics and Microbiology Esther Julián, announced one year ago that the cells of the Mycobacterium brumae offer an improved alternative to current bladder cancer treatments such as BCG (an … [Read more...]
Faulty genetic instructions drive a deadly blood cancer in adults
Scientists have previously identified a series of genetic errors that commonly occur inside cancerous blood cells, but it hasn't been clear exactly how those genetic malfunctions create immature blood cells that overpopulate, crowd out healthy cells and spread in patients with acute myeloid leukemia or AML. Now, researchers at the University of North Carolina Lineberger … [Read more...]
Understanding the resistance to treatments against breast cancer
Estrogens are responsible for the survival and proliferation of tumor cells in 70% of all breast cancer cases. The most frequently used treatment to fight this variety of tumors relies on anti-estrogens such as tamoxifen. However, nearly a third of the patients develop a resistance to this type of therapy after a few years. In a study published in the journal Nucleic Acids … [Read more...]
Tumor cells develop predictable characteristics
Tumors are composed of many subpopulations of cells. A general consensus among scientists is that these subpopulations are due to random mutations. However, Moffitt Cancer Center researchers found that these assumptions may be incorrect. In a new article published in the journal Cancer Research, they report that certain subpopulations can be predicted and do not develop … [Read more...]
Obesity: The Switch for Cancer
Having established that excessive fat tissue can fuel the growth of certain cancers, researchers have turned their attention to the molecular mechanisms involved in the process in the hopes of developing new cancer treatments. The discovery of an on/off switch for a common obesity-associated malignancy could aid those efforts, report scientists from The University of … [Read more...]
Piping hot drinks can cause esophagus cancer?
Drinking piping hot coffee, tea and the caffeine-infused beverage yerba mate probably causes cancer, the World Health Organization announced Wednesday. Beverages surpassing 149 degrees Fahrenheit (65 degrees Celsius) may increase the risk of tumors in the esophagus, which resides in the chest area below the throat, according to USC's Mariana Stern and 22 other scientists … [Read more...]
Lung cancer survival rate increases by 73 percent if caught early
The UK Lung cancer screening trial (UKLS) has been successfully completed and demonstrated that patients with a high risk of developing lung cancer can be identified with early stage disease and have up to a 73% chance of surviving for five years or more. The UKLS trial was conducted by experts in the University of Liverpool. The UKLS was undertaken in partnership with … [Read more...]
Antibody-based drug helps ‘bridge’ leukemia patients to curative treatment
In a randomized Phase III study of the drug inotuzumab ozogamicin, a statistically significant percentage of patients with acute lymphoblastic leukemia (ALL) whose disease had relapsed following standard therapies, qualified for stem cell transplants. Inotuzumab ozogamicin, also known as CMC-544, links an antibody that targets CD22, a protein found on the surface of more … [Read more...]
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