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New self-injectable drug gives infertile women greater hope

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New self-injectable drug gives infertile women greater hope

– Reported, May 24, 2013

 

A high level of non-compliance of women to a regimen of a daily injectable fertility drug prior to the in-vitro fertilisation (IVF) procedure has resulted in exacerbation of the issue.

The situation was disclosed by two reproductive health experts in the UAE , when they expressed support to the entry of a Ministry of Health-approved self-injectable prescription drug into the country two weeks ago.

The two experts were Dubai Health Authority-Dubai Gynaecology & Fertility Centre director Dr Awatif Juma Al Bahar and Burjeel Hospital (Abu Dhabi)-Centre of Reproductive Medicine director Dr Human Fatemi.

Infertility is a “medical condition that impairs the body’s ability to perform the basic function of reproduction and it is often diagnosed after a couple has not conceived after one year of unprotected, well-timed intercourse or after six months if a woman is 35 or older.”

From the sidelines of the Tuesday roundtable discussions, Fatemi who is the concurrent University Hospital Brussels-Centre of Reproductive Medicine senior medical director, claimed the use of the new self-injectable drug had consequently led to the pregnancy of a woman.

“Blood tests have shown that the patient, the first in the region, is pregnant and she would undergo the ultra-sound test next week,” said Fatemi.

The administration of the new fertility drug was done at the Burjeel Hospital.

With over 13 years of experience, Al Bahar and Fatemi claimed it is the physical, emotional and psychological strain that tops the reasons why women discontinue fertility treatments.

They presented a study conducted in The Netherlands several years ago, showing that out of 384 couples who had undergone IVF treatments, 17 per cent or 65 had dropped out.

Primary reason is the stress or strain (28 per cent or 108) on women.

Al Bahar said the Dutch study demonstrated how women in general manifest the reasons for the discontinuation of the treatments.

She added that physical, emotional and psychological tensions arise, because the daily injectable treatments which are traditionally done in clinics or hospitals, had forced women “to leave their jobs” and put at bay their other daily chores or commitments.

The other causes for the steep dropout rate for women undergoing fertility daily injectables were relationship problems or divorce (11 per cent or 42), objection to the other kind of fertility treatment which is intro-cytoplasmatic sperm injection after the failed IVF treatment in women (nine per cent or 35), poor embryo quality (eight per cent or 31), and poor response or signs of ovarian aging (six per cent or 23).

“Unknown reasons” ranked second with 25 per cent or 96.

Al Bahar and Fatemi said fertility treatments have to be made simpler.

Both added that even if the infertility issue concerns the man due to poor quality or low sperm count, “the woman must also be taken care of because the embryos would be implanted into their womb.” Fatemi described the new self-injectable drug, manufactured by MSD, as revolutionary because a single inoculation had been proven to lead to successful pregnancies.

The results had been published in the European media entity of “Human Reproduction” and the US’ “Fertility Sterility,” among other online media outlets.

Fatemi explained that the traditional way of fertility injectable treatments, which comes in single to triple inoculations, are taken on a daily basis between 10 and 30 days to help a woman ovulate.
 

In IVF, the eggs, after the successful ovulation, are combined with the sperms, hopefully to produce an embryo or embryos within 24 hours and which are implanted back to the woman’s womb.

CREDITS.

http://gulftoday.ae/      

 

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