Running, cycling, or swimming -- if you regularly exercise, you're well on track for a long and healthy life, as groundbreaking new research from the University of South Australia finds that an increased cardio fitness level will reduce your risk of death from any cause by 11-17%. Published in BJSM, the study found that for every 1-MET increase in cardiorespiratory fitness … [Read more...]
Physical Activity in Nature Helps Prevent Several Diseases, Including Depression and type 2 Diabetes
Physical activity in natural environments prevent almost 13,000 cases of non-communicable diseases a year in England and save treatment costs of more than £100m, new research from the University of Exeter has found. According to the World Health Organization (WHO) the most common non-communicable diseases -- including heart disease, stroke, cancer, diabetes, and chronic … [Read more...]
Researchers Identify Causal Genetic Variant Linked to Common Childhood Obesity
Both environmental and genetic factors play critical roles in the increasing incidence of childhood obesity. While the exact role of genetics in childhood obesity is still not fully understood, prior studies show that neuronal pathways in the hypothalamus control food intake and are key regulators for the disease. Prior international genome-wide association studies (GWAS) … [Read more...]
Cranberry Extracts Could Boost Microbiota and Counter Cardiometabolic Diseases
Cranberries and berries are associated with multiple health benefits, mainly attributed to their high content of polyphenols, in the form of tannins. They also contain high concentrations of oligosaccharides, small fibres that are thought to contribute to their bioactivity. The research team, led by Yves Desjardins, professor at the Faculty of Agriculture and Food … [Read more...]
Pan-Cancer Analysis Uncovers a New Class of Promising CAR T-Cell Immunotherapy Targets
Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T-cell immunotherapy, where a patient's own immune cells are re-engineered to attack cancer cells, many solid and brain cancers lack an effective target. St. Jude Children's Research Hospital scientists have identified 156 potential targets through a … [Read more...]
Cranberries Provide Runners With an all-Natural Boost
Competitive athletes are always looking for an extra edge that can help them improve performance. According to a new study by Concordia researchers published in the journal Physical Activity and Nutrition, they can find one in the common cranberry. In a series of trials involving trained distance runners, the researchers found that ingesting a cranberry supplement for 28 … [Read more...]
Kallistatin Contributes to the Beneficial Metabolic Effects of Weight Loss
An increasing number of people are developing type 2 diabetes and obesity. These are highly complex and multifaceted diseases. In order to treat them sustainably, new approaches to therapy are needed. Clinical studies on humans have shown that heavily overweight individuals produce less Kallistatin.Kallistatin is a protein that has various effects in the body. Among other … [Read more...]
The Impact of the Family Dog on The Exercise Habits of Kids.
With two-thirds of children in the U.S. failing to meet national physical activity guidelines, kinesiologists at the University of Massachusetts Amherst have been looking at the impact of the family dog on the exercise habits of kids. Could having a canine best friend get kids on their feet and help bring them more in line with the minimum recommendation of 60 minutes of … [Read more...]
Healthy Diets Increase The Economic and Physical Feasibility of 1.5°C
A global shift to a healthier, more sustainable diet could be a huge lever to limit global warming to 1.5°C, researchers at the Potsdam Institute for Climate Impact Research (PIK) find. The resulting reduction of greenhouse gas emissions would increase the available carbon budget compatible with limiting global warming to 1.5°C, and allow to achieve the same climate outcome … [Read more...]
Eggs May not be Bad for Your Heart After all
Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial presented at the American College of Cardiology's Annual Scientific Session show that over a four-month period cholesterol levels were similar among … [Read more...]
Making Long-Term Memories Requires Nerve-Cell Damage
"Inflammation of brain neurons is usually considered to be a bad thing, since it can lead to neurological problems such as Alzheimer's and Parkinson's disease," said study leader Jelena Radulovic, M.D., Ph.D., professor in the Dominick P. Purpura Department of Neuroscience, professor of psychiatry and behavioral sciences, and the Sylvia and Robert S. Olnick Chair in … [Read more...]
Anxiety and Depression Could Offer an Early Warning of Cardiovascular Risk
Younger women are generally thought to have a low risk of heart disease, but new research urges clinicians to revisit that assumption, especially for women who suffer from certain mental health conditions. A new study being presented at the American College of Cardiology's Annual Scientific Session found that having anxiety or depression could accelerate the development of … [Read more...]
Do Sweeteners Increase Your Appetite? New Evidence From Randomised Controlled Trial Says no
Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier -- and also helps to reduce blood sugar levels, a significant new study has found. The double blind randomised controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods … [Read more...]
Researchers a Step Closer To a Cure For HIV
In a first, the study published in the journal Emerging Microbes and Infections demonstrated the team's patented therapeutic candidate, an HIV-virus-like-particle (HLP), is 100 times more effective than other candidate HIV cure therapeutics for people living with chronic HIV on combined antiretroviral therapy (cART). If successful in clinical trials, HLP could be used by … [Read more...]
Beating By Overheating: New Strategy to Combat Cancer
To treat cancer, you have to inhibit cancer cells. Right? Researchers at the Netherlands Cancer Institute did just the opposite. They achieved surprising results by overstimulating cancer cells in the lab and then hitting them at their weak spot: stress. "This goes against the prevailing view." Many new drugs inhibit the processes that cancer cells need to divide rapidly. So … [Read more...]
Gut Bacteria Important For Overcoming Milk Allergy
Many children have allergic reactions to cow's milk, specifically to certain milk proteins. Although most grow out of it, for some it becomes a life-long challenge to avoid all foods that include milk, especially when the allergic reactions are severe and include anaphylactic shock. Researchers have found that milk allergy is improved by oral immunotherapy, a treatment in … [Read more...]
Genes Dictate Taste: Study Finds Genetic Links to Food Preferences
In the present systematic review, researchers evaluated the genetic influence on dietary preferences among adults. In August 2022, the team searched the Cochrane Library, Scopus, PubMed, Web of Science, Embase, OpenGrey, and ClinicalTrials.gov databases for relevant studies evaluating the impact of genotypes on food choices, preferences, and intake among healthy adults, … [Read more...]
Flexitarian Diet Linked to Lower Cardiovascular Risk, Study Finds
A new study published in BMC Nutrition examines the cardiovascular risk associated with different dietary patterns. About the study Study participants between 25 and 45 years old were divided into three groups. The first group comprised long-term flexitarians (FXs) who ingested 50 grams of meat or meat products each day, whereas the second group consisted of vegans who … [Read more...]
Ketogenic Diet: Role in Curbing Cravings in Alcohol use Disorder Patients
In a recent study published in the journal Frontiers in Nutrition, a group of researchers investigated whether a ketogenic diet (KD) reduces a neurobiological craving signature (NCS) and self-reported alcohol wanting in patients undergoing inpatient treatment for alcohol use disorder (AUD). About the study: The present study provides a secondary analysis of functional … [Read more...]
New Study Reveals Black Pregnant Individuals’ Preference for Black Obstetric Care Providers
Data from the Centers for Disease Control and Prevention demonstrate that Black women in the United States are three times more likely to die from a pregnancy-related cause than are white women. Health disparities among people of color are the result of broader social and economic inequities rooted in racism and discrimination. In a new study to be presented today at the … [Read more...]
Gut Microbiota Influence Severity of Respiratory Viral Infection
The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, according to researchers from the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University. The findings, published in the journal Cell Host & Microbe, report that … [Read more...]
Understanding Rapid Weight Loss in Older Women: Message From the Heart
Unexplained rapid weight loss in older people could be a sign of underlying disease and can be linked with increased risk of falls and fractures, as well as a poorer long-term prognosis. The understanding of factors that could contribute to rapid weight loss remains poor, with current treatments including correcting suboptimal dietary and physical activity behaviors. New … [Read more...]
New Weight Loss Medication may help Lower Blood Pressure in Adults with Obesity
The new weight loss medication tirzepatide significantly lowered the systolic blood pressure (the top number in a blood pressure reading) for nearly 500 adults with obesity who took the medication for about eight months, according to new research published today in Hypertension, an American Heart Association journal. Systolic blood pressure, or the top number in the blood … [Read more...]
Hand-Held Biosensor Makes Breast Cancer Screening Fast, Affordable, And Accurate
Breast cancer is on the rise, but new tools for early detection could save lives. In Journal of Vacuum Science & Technology B, by AIP Publishing, researchers from the University of Florida and National Yang Ming Chiao Tung University in Taiwan reported successful results from a hand-held breast cancer screening device that can detect breast cancer biomarkers from a … [Read more...]
Non-Invasive Techniques to Detect Skin Cancer
A study conducted by Aston University researchers has demonstrated that the appearance of ageing skin looks noticeably different compared to younger skin, when examined under polarised laser light. The scientists believe that their new finding could pave the way for new, non-invasive light-based techniques to detect diseases, including cancer, in older individuals. This … [Read more...]
Key to Healing Injured Hearts
A groundbreaking scientific study published in Nature Cardiovascular Research has unveiled a remarkable discovery that may have far-reaching implications for the treatment of heart disease. The intensive investigations utilizing single-cell genomics and genetic experiments were conducted by a team of scientists in theCardiomyocyte Renewal Laboratory and McGill Gene Editing … [Read more...]
Cold Water Swimming Improves Menopause Symptoms
Menopausal women who regularly swim in cold water report significant improvements to their physical and mental symptoms, finds a new study led by UCL researchers. The research, published in Post Reproductive Health, surveyed 1114 women, 785 of which were going through the menopause, to examine the effects of cold water swimming on their health and wellbeing. The findings … [Read more...]
New Model Predicts How Shoe Properties Affect a Runner’s Performance
A good shoe can make a huge difference for runners, from career marathoners to couch-to-5K first-timers. But every runner is unique, and a shoe that works for one might trip up another. Outside of trying on a rack of different designs, there's no quick and easy way to know which shoe best suits a person's particular running style. MIT engineers are hoping to change that with … [Read more...]
Furry fruit improves mental health — fast
Kiwifruit has proven itself as a powerful mood booster and new research from the University of Otago has shown just how fast its effects can be. In a study, published in The British Journal of Nutrition, researchers found the furry fruit improved vitality and mood in as little as four days. Co-author Professor Tamlin Conner, of the Department of Psychology, says the … [Read more...]
Women Exposed to Toxic Metals may Experience Earlier Aging of Their Ovaries
Middle-aged women who are exposed to toxic metals may have fewer eggs in their ovaries as they approach menopause, according to new research published in The Journal of Clinical Endocrinology & Metabolism. Diminished ovarian reserve is when women have fewer eggs compared to others their age. The condition may be linked to health problems such as hot flashes, weak … [Read more...]
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