(Ivanhoe Newswire) -- New research reveals testosterone may be a key
factor when it comes to spreading diseases. The study was done in mice, but
researchers say the findings help explain why males are more likely to get
infected and transmit disease.
Testosterone is the male sex hormone. Previous studies have linked testosterone
to immune system suppression. Researchers from Penn State say while they know
testosterone makes males more susceptible to disease, they also wanted to
understand if it affects their behavior and how that increases their ability to
transmit disease.
For the study, investigators raised the testosterone levels in wild mice and
then measured the disease risk they posed to the population. They treated 24
male mice trapped in five sites. Twenty-five other male mice received sham
implants and mice at three other sites received neither treatment. All sites
were trapped twice a week for six weeks before and after treatment. All of the
mice were electronically tagged to see where they were trapped. This gave
researchers a good picture of how the treated and untreated mice mixed over
time.
Study authors say they found the mice were mixing more when the testosterone
treated mice were present. “These findings suggest that even if some individuals
in a population have high levels of testosterone, they can impact the behavior
of those around, and drive the transmission of diseases transmitted by close
contact such as the respiratory pathogen bordetella,” says Daniel Grear, Penn
State doctoral student in ecology.
SOURCE: Presented at the annual meeting of the Ecological Society of America in
Milwaukee, Wisconsin on August 8, 2008