FRIDAY, Aug. 1 (HealthDay News) — For women who find traditional
mammograms painful, new research suggests there may one day be a more
comfortable alternative.
Breast CT scans showed some advantages over traditional mammograms, said study
author John Boone, vice chairman of radiology at the University of California
Davis Medical Center. He presented the findings this week at the American
Association of Physicists in Medicine annual meeting, in Houston.
"Breast cancer shows up on a mammogram or imaging in two different ways — a mass
lesion or a spot," Boone explained. These spots are called microcalcifications,
and they can signal the beginnings of a tumor.
In the CT breast exam, the scanner rotates around the breast to create a
three-dimensional picture of the breast. The total radiation dose in the scan
Boone used is the same as in a conventional mammogram, he said. In this study,
160 women were screened this way.
But the breasts are not compressed between plates, as in a traditional
mammogram. Instead, the woman lies face down on a special table with one breast
suspended through an opening.
"We feel the breast CT was superior to traditional mammography for mass lesions,
but mammography remains superior over breast CT for microcalcifications," he
said.
Several other centers are also studying breast CT, he noted. The role of breast
CT is evolving, Boone said, and will depend on continuing research and how it
bears out.
In his research, Boone and his colleagues have also
began to study another prototype device which
incorporates a positron emission tomography (PET)
scanner into the CT scanner. The PET scanner can track
the metabolic activity of a tumor, if present, so
doctors can pinpoint the tumor and evaluate the effect
of treatment.
Breast CT scans may be widely available in three to five years, Boone predicted.
The technology is experimental, cautioned Robert Smith, director of cancer
screening for the American Cancer Society. "One of the things that is appealing
is comfort on the part of the patient," he said.
But, he added, if it is going to play a role in breast imaging, "it has to be
just as accurate in finding breast cancer [as mammography], and should not
generate a higher rate of false positives."
In other presentations at the meeting, University of Wisconsin researchers
reported on improvements in tools to make a procedure called modulated electron
therapy (MERT) more effective in treating tumors of the chest wall after
mastectomy.
And University of Chicago researchers discussed a new automated computer image
analysis technique that better characterizes and diagnoses early breast cancers.
The computer program makes use of facts known about how lesions respond to
injected contrast agents to help doctors describe the lesion's characteristics.
For instance, malignant lesions wash out contrast material more quickly than
benign ones.
SOURCES: John M. Boone, Ph.D., professor and vice chairman, radiology, and
professor, biomedical engineering, University of California Davis Medical
Center, Sacramento; Robert Smith, Ph.D., director, breast cancer screening,
American Cancer Society, Atlanta; July 27-31, 2008, presentations, American
Association of Physicists in Medicine annual meeting, Houston
